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Axsome Therapeutics
Axsome Therapeutics
(AXSM)
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Clinical Trials
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Revenue by Drug
Marketed Drugs
Therapeutic Areas:
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Classification:
All
Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Auvelity
Bupropion
,
Dextromethorphan
2022-08-18
2023-2040
Atrial fibrillation
,
Atrial flutter
,
Cardiac arrhythmias
,
Cough
,
Neurobehavioral manifestations
,
Sinusitis
,
Asthma
,
Common cold
,
Allergic rhinitis perennial
,
Urticaria
,
Vasomotor rhinitis
,
Whooping cough
,
Bronchitis
,
Pharyngitis
,
Laryngitis
,
Postoperative complications
,
Pain
,
Vomiting
,
Nausea
,
Anaphylaxis
,
Allergic conjunctivitis
,
Motion sickness
,
Tobacco use disorder
,
Attention deficit disorder with hyperactivity
,
Depressive disorder
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Dextromethorphan
healthy volunteers/patients
,
schizophrenia
,
depression
,
treatment-resistant depressive disorder
,
major depressive disorder
,
depressive disorder
,
dyskinesias
,
psychomotor agitation
,
multiple sclerosis
,
neuralgia
,
migraine disorders
,
disease progression
,
parkinson disease
,
sclerosis
,
amyotrophic lateral sclerosis
,
pain
,
diabetic neuropathies
,
motor neuron disease
,
pseudobulbar palsy
,
alzheimer disease
,
stroke
,
traumatic brain injuries
,
brain injuries
,
dementia
Bupropion
type 2 diabetes mellitus
,
hiv infections
,
seasonal affective disorder
,
bipolar disorder
,
psychological sexual dysfunctions
,
crohn disease
,
epilepsy
,
lethargy
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
mood disorders
,
depressive disorder
,
major depressive disorder
,
depression
,
smoking cessation
,
mental disorders
,
problem behavior
,
chronic obstructive pulmonary disease
,
obstructive lung diseases
,
breast neoplasms
,
dysthymic disorder
,
tobacco use disorder
,
cardiovascular diseases
,
myocardial infarction
,
unstable angina
,
infarction
,
smoking
,
congenital abnormalities
,
pregnancy
,
neoplasms
Glutamic acid
carcinoma
,
non-small-cell lung carcinoma
,
lung neoplasms
Doconexent
restless legs syndrome
,
psychomotor agitation
,
neoplasms
,
uterine cervical neoplasms
,
depression
,
multiple myeloma
,
hematologic diseases
,
blood protein disorders
,
plasma cell neoplasms
,
paraproteinemias
,
corneal diseases
,
drug resistance
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
sarcoma
,
synovial sarcoma
,
falciparum malaria
,
heat stress disorders
,
mood disorders
,
combat disorders
,
traumatic stress disorders
,
covid-19
,
healthy volunteers/patients
,
proteinuria
,
focal segmental glomerulosclerosis
,
sickle cell anemia
,
beta-thalassemia
,
thalassemia
,
sickle cell trait
,
myocardial infarction
,
infarction
,
human influenza
,
malaria
,
breast neoplasms
,
vivax malaria
,
rheumatoid arthritis
,
arthritis
,
asthma
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
heart failure
,
hypertriglyceridemia
,
atrial fibrillation
,
virus diseases
,
inflammation
,
tick-borne encephalitis
,
encephalitis
,
hiv infections
,
rabies
,
mitochondrial diseases
,
mitral valve insufficiency
,
hypertrophy
,
liver diseases
,
non-alcoholic fatty liver disease
,
fatty liver
,
wasting syndrome
,
cachexia
,
nasal polyps
,
polyps
,
infections
,
cytomegalovirus infections
,
communicable diseases
,
gastrointestinal diseases
,
digestive system diseases
,
depressive disorder
Esreboxetine
healthy volunteers/patients
,
fecal incontinence
,
substance-related disorders
,
amphetamine-related disorders
,
mood disorders
,
urinary incontinence
,
stress urinary incontinence
,
enuresis
,
peripheral nervous system diseases
,
neuralgia
,
postherpetic neuralgia
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
diabetic neuropathies
,
post-traumatic stress disorders
,
traumatic stress disorders
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
fibromyalgia
,
myofascial pain syndromes
,
narcolepsy
,
cataplexy
,
sleepiness
,
disorders of excessive somnolence
,
dementia
,
psychophysiologic disorders
,
anxiety disorders
,
somatoform disorders
,
fatigue
,
pain
,
depression
,
major depressive disorder
,
depressive disorder
,
schizophrenia
,
abdominal pain
,
hypersensitivity
,
stroke
,
panic disorder
,
decision making
Reboxetine
fecal incontinence
,
substance-related disorders
,
amphetamine-related disorders
,
mood disorders
,
urinary incontinence
,
stress urinary incontinence
,
enuresis
,
peripheral nervous system diseases
,
neuralgia
,
postherpetic neuralgia
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
diabetic neuropathies
,
post-traumatic stress disorders
,
traumatic stress disorders
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
fibromyalgia
,
narcolepsy
,
cataplexy
,
sleepiness
,
myofascial pain syndromes
,
disorders of excessive somnolence
,
dementia
,
psychophysiologic disorders
,
anxiety disorders
,
somatoform disorders
,
fatigue
,
pain
,
depression
,
major depressive disorder
,
depressive disorder
,
schizophrenia
,
abdominal pain
,
hypersensitivity
,
stroke
,
panic disorder
,
healthy volunteers/patients
,
decision making
Tiratricol
infections
,
hiv infections
,
acquired immunodeficiency syndrome
,
healthy volunteers/patients
,
common cold
,
drug interactions
,
cognitive dysfunction
,
cognition disorders
,
neurocognitive disorders
,
type 2 diabetes mellitus
,
diabetes mellitus
,
back pain
,
anaphylaxis
D-glutamate
obesity
,
prostatic neoplasms
,
hepatocellular carcinoma
,
positron-emission tomography
,
pharmacokinetics
,
severe acute respiratory syndrome-related coronavirus
,
pervasive child development disorders
,
human influenza
,
consciousness disorders
,
osteosarcoma
,
large cell carcinoma
,
coronavirus infections
,
middle east respiratory syndrome coronavirus
,
marijuana use
,
gastrointestinal diseases
,
digestive system diseases
,
colitis
,
neurilemmoma
,
cholangiocarcinoma
,
sleepiness
,
herpes simplex
,
radiation dosimeters
,
treatment-resistant schizophrenia
,
obsessive-compulsive disorder
,
compulsive personality disorder
,
pancreatic neoplasms
,
breast neoplasms
,
recurrence
,
neoplasms
,
stroke
,
autistic disorder
,
triple negative breast neoplasms
,
cigarette smoking
,
hiv infections
,
heart arrest
,
dementia
,
autism spectrum disorder
,
acidosis
,
propionic acidemia
,
marijuana abuse
,
hyperkinesis
,
alzheimer disease
,
urologic neoplasms
,
neoplasm metastasis
,
beta-thalassemia
,
thalassemia
,
adenocarcinoma of lung
,
movement disorders
,
borderline personality disorder
,
personality disorders
,
hyperammonemia
,
autoimmune diseases
,
prediabetic state
,
multiple pulmonary nodules
,
solitary pulmonary nodule
,
cannabis
,
fragile x syndrome
,
persistent infection
,
multiple sclerosis
,
impulsive behavior
,
mood disorders
,
suicide
,
glioblastoma
,
squamous cell neoplasms
,
non-hodgkin lymphoma
,
squamous cell carcinoma of head and neck
,
melanoma
,
merkel cell carcinoma
,
hidradenitis suppurativa
,
hidradenitis
,
multiple myeloma
,
plasma cell neoplasms
,
head and neck neoplasms
,
brain edema
,
neurodegenerative diseases
,
small cell lung carcinoma
,
bronchiolo-alveolar adenocarcinoma
,
alcohol-related disorders
,
latent autoimmune diabetes in adults
,
pancreatic ductal carcinoma
,
dyskinesias
,
asthma
,
respiratory sounds
,
self-injurious behavior
,
dyslexia
,
developmental disabilities
,
asperger syndrome
,
craniocerebral trauma
,
ornithine carbamoyltransferase deficiency disease
,
carbamoyl-phosphate synthase i deficiency disease
,
deficiency diseases
,
inborn errors amino acid metabolism
,
vitamin d deficiency
,
glucose metabolism disorders
,
metabolic diseases
,
immune system diseases
,
metabolic syndrome
,
endocrine system diseases
,
renal cell carcinoma
,
b-cell lymphoma
,
nutrition disorders
,
alcohol withdrawal delirium
,
huntington disease
,
chorea
,
drinking behavior
,
small fiber neuropathy
,
inborn urea cycle disorders
,
out-of-hospital cardiac arrest
,
aggression
,
brain concussion
,
post-concussion syndrome
,
carcinoma in situ
,
cervical intraepithelial neoplasia
,
uterine cervical dysplasia
,
trichotillomania
,
paramyxoviridae infections
,
salivary gland neoplasms
,
adenoid cystic carcinoma
,
digeorge syndrome
,
22q11 deletion syndrome
,
frontotemporal dementia
,
primary progressive aphasia
,
pick disease of the brain
,
anorexia
,
anorexia nervosa
,
hemoglobinopathies
,
lewy body disease
,
behavioral symptoms
,
lung neoplasms
,
non-small-cell lung carcinoma
,
healthy volunteers/patients
,
carcinoma
,
treatment-resistant depressive disorder
,
diabetes mellitus
,
type 1 diabetes mellitus
,
brain injuries
,
traumatic brain injuries
,
ovarian neoplasms
,
epilepsy
,
malignant mesothelioma
,
mesothelioma
,
ischemic stroke
,
attention deficit disorder with hyperactivity
,
ovarian epithelial carcinoma
,
adenocarcinoma
,
fallopian tube neoplasms
,
cerebral infarction
,
tuberculosis
,
squamous cell carcinoma
,
transitional cell carcinoma
,
colorectal neoplasms
,
hypertension
,
rett syndrome
,
covid-19
,
status epilepticus
,
lymphoma
,
chronic pain
,
brenner tumor
,
endometrioid carcinoma
,
mucinous cystadenocarcinoma
,
serous cystadenocarcinoma
,
peritoneal neoplasms
,
cystadenocarcinoma
,
drug resistant epilepsy
,
infarction
,
coronary artery bypass
,
arthritis
,
chikungunya fever
,
ataxia
,
spinocerebellar degenerations
,
spinocerebellar ataxias
,
machado-joseph disease
,
cerebellar ataxia
,
mucinous adenocarcinoma
,
clear cell adenocarcinoma
,
acinar cell carcinoma
,
leukemia
,
sarcoma
,
kidney neoplasms
,
neurotoxicity syndromes
,
latent tuberculosis
,
tendinopathy
,
rotator cuff injuries
,
inborn genetic diseases
,
heart failure
,
postoperative complications
,
prostatitis
,
chronic disease
,
pelvic pain
,
somatoform disorders
,
myocardial infarction
,
coronary disease
,
coronary artery disease
,
hemorrhage
,
subarachnoid hemorrhage
,
brain ischemia
,
intracranial vasospasm
,
emergence delirium
,
depressive disorder
,
depression
,
major depressive disorder
,
schizophrenia
,
bipolar disorder
,
syndrome
,
alcoholism
,
psychotic disorders
,
parkinson disease
,
cocaine-related disorders
,
cognitive dysfunction
,
mental disorders
,
herpes zoster
,
chickenpox
,
alcohol drinking
,
wounds and injuries
,
inflammation
,
brain neoplasms
,
ischemia
,
infections
,
communicable diseases
,
peripheral nervous system diseases
,
nervous system diseases
,
addictive behavior
,
anxiety disorders
,
seizures
,
anxiety
,
hypertrophy
,
myocardial ischemia
,
neurologic gait disorders
,
fatigue
,
tourette syndrome
,
cognition disorders
,
neurocognitive disorders
,
heart transplantation
,
keratoconjunctivitis
,
allergic conjunctivitis
,
substance withdrawal syndrome
,
suicidal ideation
,
inguinal hernia
,
hernia
,
morbidity
,
sleep initiation and maintenance disorders
,
respiratory tract infections
,
hyperplasia
,
left ventricular hypertrophy
,
cardiopulmonary bypass
,
aortic valve stenosis
,
hypersensitivity
,
dentin sensitivity
,
calcium metabolism disorders
,
vertigo
,
dizziness
,
hepatitis a
,
burns
,
pain
,
problem behavior
,
migraine disorders
,
post-traumatic stress disorders
,
traumatic stress disorders
,
irritable bowel syndrome
,
systemic lupus erythematosus
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
restless legs syndrome
,
psychomotor agitation
,
healthy diet
,
pulmonary hypertension
,
hemolysis
,
exploratory behavior
,
neuralgia
,
diabetic neuropathies
,
gender dysphoria
,
insulin resistance
,
diet
,
randomized controlled trials as topic
,
abdominal neoplasms
,
temporal lobe epilepsy
,
atrial fibrillation
,
chronic obstructive pulmonary disease
,
lung diseases
,
keratitis
,
autoimmune hepatitis
,
autoimmune polyendocrinopathies
,
glioma
,
cytokine release syndrome
,
sepsis
,
septic shock
,
toxemia
,
stiff-person syndrome
,
growth disorders
,
conduct disorder
,
sarcopenia
,
headache disorders
,
headache
,
central nervous system diseases
,
brain diseases
,
migraine without aura
,
primary headache disorders
,
autoimmunity
,
cognitive neuroscience
,
tic disorders
,
paraneoplastic syndromes
,
hyponatremia
,
persian gulf syndrome
,
diet therapy
,
atherosclerosis
,
encephalitis
,
infectious encephalitis
,
reperfusion injury
,
gastroparesis
,
amphetamine-related disorders
,
hypoxia
,
brain hypoxia
,
central nervous system lupus vasculitis
,
pure autonomic failure
,
shy-drager syndrome
,
multiple system atrophy
,
weight gain
,
food preferences
,
bacterial infections
,
clostridium infections
,
clostridioides difficile
,
gastroesophageal reflux
,
substance-related disorders
,
myofascial pain syndromes
,
fibromyalgia
,
type 2 diabetes mellitus
,
hypernatremia
,
dysbiosis
,
patient participation
,
acne vulgaris
,
skin aging
,
liver neoplasms
,
liver transplantation
,
hypothermia
,
tobacco use disorder
,
sex
,
deep brain stimulation
,
cortical excitability
Buproprion
healthy volunteers/patients
,
bipolar disorder
,
binge drinking
,
second primary neoplasms
,
alcoholism
,
non-small-cell lung carcinoma
,
lung neoplasms
,
mood disorders
,
hiv infections
,
substance-related disorders
,
smoking cessation
,
smoking
,
treatment-resistant depressive disorder
,
alzheimer disease
,
dementia
,
crohn disease
,
huntington disease
,
chorea
,
depressive disorder
,
major depressive disorder
,
depression
,
tobacco use disorder
Wellbutrin
type 2 diabetes mellitus
,
hiv infections
,
seasonal affective disorder
,
bipolar disorder
,
psychological sexual dysfunctions
,
crohn disease
,
epilepsy
,
lethargy
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
mood disorders
,
depressive disorder
,
major depressive disorder
,
depression
,
smoking cessation
,
mental disorders
,
problem behavior
,
chronic obstructive pulmonary disease
,
obstructive lung diseases
,
breast neoplasms
,
dysthymic disorder
,
tobacco use disorder
,
cardiovascular diseases
,
myocardial infarction
,
unstable angina
,
infarction
,
smoking
,
congenital abnormalities
,
pregnancy
,
neoplasms
Nicoderm
graft vs host disease
,
bronchiolitis obliterans syndrome
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